(3-chlorothiophen-2-yl)boronic acid

(3-chlorothiophen-2-yl)boronic acid - Names and Identifiers

Name	3-Chlorothiophene-2-boronic acid
Synonyms	(3-chloro-2-thienyl)boronic acid 3-Chlorothiophene-2-boronic acid 3-CHLOROTHIOPHENE-2-BORONIC ACID (3-chlorothiophen-2-yl)boronicaci (3-chlorothiophen-2-yl)boronic acid Boronic acid, B-(3-chloro-2-thienyl)-
CAS	324024-80-8

(3-chlorothiophen-2-yl)boronic acid - Physico-chemical Properties

Molecular Formula	C4H4BClO2S
Molar Mass	162.4
Density	1.50±0.1 g/cm3(Predicted)
Boling Point	334.1±52.0 °C(Predicted)
pKa	8.12±0.58(Predicted)
Storage Condition	Sealed in dry,Store in freezer, under -20°C

(3-chlorothiophen-2-yl)boronic acid - Introduction

acid is an organic compound with the chemical formula C4H3BClOS. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
A colorless to light yellow crystalline solid. It is less soluble in water, but soluble in many organic solvents, such as ethanol, dimethylformamide and dichloromethane. The compound is relatively stable in air and does not readily decompose under regular storage conditions.

Use:
acid has a wide range of applications, especially suitable for organic synthesis reactions. It can be used as a catalyst, ligand or intermediate in organic synthesis. The compound is commonly used in chemical reactions to build carbon-boron compounds, such as Suzuki coupling reactions, which can be reacted with other compounds to synthesize organic molecules with specific functions.

Method:
The preparation of Calcium acid is usually carried out by the following steps: First, 3-Chlorothiophene (3-Chlorothiophene) is obtained, and then it is reacted with boric acid under alkaline conditions. After the reaction, the target product is obtained by a separation and purification method such as crystallization or column chromatography.

Safety Information:
Limited information is available on toxicology and safety of. Since this compound is often used as a catalyst or intermediate in organic synthesis, it should be used in accordance with laboratory safety procedures. Avoid contact with skin and eyes, pay attention to protective measures. According to the characteristics of the chemical, it is best to use it in a well-ventilated place and avoid inhaling aerosols or inhaling dust. In case of accidental ingestion or inhalation, seek medical advice immediately. Relevant safety technical data and MSDS (chemical material safety data sheet) should be properly kept and consulted.

Last Update：2024-04-10 22:29:15